在肝胆瘤中术后感染:第三级护理中心的经验
Basant Mahaddevappa1, Rohith Muddasetty1, Vinu Sankar V S1
1Hepatopancreatobiliary Surgery and Liver Transplantation, Health Care Global (HCG) Hospital, Bangalore, IND.
Cureus
|September 15, 2023
概括
在肝胆瘤手术中进行手术前的支架显著增加了胆汁中的细菌生长,增加了伤口感染的风险. 这导致更长的住院时间和延迟的辅助治疗,需要在支架之前仔细考虑.
科学领域:
- 肝肝胆道手术 肝肝胆道手术
- 手术瘤学手术瘤学
- 传染性疾病 传染性疾病
背景情况:
- 伤口感染是肝胆瘤手术后的常见并发症.
- 诸如糖尿病,手术持续时间,血液损失和先前支架等因素有助于感染风险.
- 阻塞性黄在这些癌症中很常见,通常通过术前支架进行管理,这种做法具有争论的术后结果.
研究的目的:
- 调查手术前支架对胆汁中的细菌生长和随后的伤口感染风险的影响,在接受胆道肠道解剖的患者中.
- 为了确定影响瘤手术中术后伤口感染的关键因素.
主要方法:
- 在2013年1月至2023年6月期间,对150名接受了涉及胆道肠道解剖手术的患者进行了回顾性分析.
- 采用二进制回归分析来评估术前支架,胆汁中的细菌生长和伤口感染之间的关联.
- 使用统计测试来确定各种参数的显著程度.
主要成果:
- 手术前的支架与胆汁中细菌生长的风险增加了12倍 (OR:12,95% CI:5.25-27.42,p<0.001).
- 胆汁中细菌的存在使伤口感染的风险增加了16.5倍 (OR: 45,95% CI: 7-38.89,p<0.001).
- 患有伤口感染的患者在医院住院时间明显长,治疗费用增加,辅助治疗推迟.
结论:
- 手术前的支架和长时间的手术时间增加了胆汁中的细菌生长,增加了手术伤口感染的风险.
- 这些患者的伤口感染导致长时间住院,并妨碍及时启动辅助治疗.
- 在多学科瘤委员会讨论后,应对肝胆瘤恶性瘤进行手术前支架决定.
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