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长期的环境丰富与老年人更好的体微观结构有关

Olga M Klimecki¹, Maxie Liebscher¹, Malo Gaubert^1,2

¹German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.

Frontiers in aging neuroscience

|September 15, 2023

概括

通过各种休活动进行终身环境丰富 (EE),可以保持大脑记忆系统中的白质微观结构. 这表明,在老年人中,丰富的生活方式和更好的认知健康之间存在联系.

科学领域:

神经科学是一个神经科学.
认知老龄化认知老龄化
公共卫生公共卫生

背景情况:

通过通过各种休活动持续丰富环境 (EE),可以降低阿尔茨海默病的风险.
这项研究研究了老年人长期EE和记忆系统纤维通道微观结构之间的联系.

研究的目的:

研究长期环境丰富 (EE) 与老年人记忆系统中的白质微观结构之间的关联.
探索终身休活动与与记忆相关的大脑结构之间的关系.

主要方法:

对201名认知能力不受损的老年人 (≥60岁) 的横截面队列研究.
参与者根据休活动频率 (13-65岁) 被分为更高或更低的长期EE组.
用扩散张力成像测量的,未切割的和近海马环膜的白物质微观结构 (FA,MD).

主要成果:

更高的长期EE与增强的骨微观结构 (更高的FA,更低的MD) 有关.
改善的福尼克斯微观结构,与更高的EE相关,间接与更好的记忆功能相关.
在其他白质区域没有观察到显著的影响.

结论:

持续参与各种休活动与记忆系统中保存的白质微观结构有关.
在身体,智力和社会上丰富的生活方式可能会支持老化中的大脑健康.
需要进一步的纵向研究来证实这些发现.

关键词:

阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.大脑的可塑性大脑的可塑性.大脑储备储备是什么?记忆记忆记忆记忆记忆多式休活动多式休活动.预防预防预防

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