一个Yuma myotis蝙蝠,Myotis yumanensis的基因组组合
Joseph N Curti1, Devaughn Fraser2, Merly Escalona3
1Department of Ecology and Evolutionary Biology, University of California, Los Angeles (UCLA), Los Angeles, CA, United States.
The Journal of heredity
|September 15, 2023
概括
研究人员开发了第一个Yuma myotis蝙蝠 (Myotis yumanensis) 基因组组. 这种至关重要的资源有助于保护工作,特别是追踪对白鼻综合征的反应.
科学领域:
- 基因组学就是基因组学.
- 保护生物学 保护生物学
- 哺乳动物学 哺乳动物学
背景情况:
- 尤马蝙蝠 (Myotis yumanensis) 容易患上白鼻综合征.
- 有限的基因组资源阻碍了对敏感的蝙蝠物种的保护管理.
- 在12种被白鼻综合征影响的蝙蝠物种中,只有两种有可用的基因组资源.
研究的目的:
- 为了生成第一个 de novo 基因组组合的尤玛蝙蝠 (Myotis yumanensis).
- 为保护和进化研究提供高质量的基因组资源.
- 为了支持追踪蝙蝠群体对白鼻综合征反应的努力.
主要方法:
- 使用PacBio HiFi的基因组组装长时间读取.
- 整合了Omni-C染色体近距离测序技术.
- 作为加利福尼亚保护基因组学项目的一部分.
主要成果:
- 首个新基因组组合Yuma myotis (Myotis yumanensis) 已经成功生成.
- 该组件质量很高,具有28.03 Mb的N50连接器和99.14 Mb的N50脚手架.
- 布斯科的完整性得分达到93.7%,表明基因组非常完整.
结论:
- 玉米的基因组组合是比较基因组学和进化研究的宝贵资源.
- 这种基因组将为保护管理策略提供信息,特别是关于白鼻综合征.
- 它使基因组方法能够监测Yuma myotis种群及其对疾病的抵抗力.
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