来自发展中国家的抗菌素处方模式的点患病率探测
Nazia Khursheed1, Qadeer Ahsan2, Salima Rattani1
1Indus Hospital and Health Network, Fleming Fund Country Grant, Karachi, Pakistan.
Expert review of anti-infective therapy
|September 15, 2023
概括
巴基斯坦的一项调查发现,抗生素的使用率很高,78.5%的住院患者接受了处方. 塞夫特里亚克松是最常见的. 这凸显了医院需要更好的抗菌药物管理计划的必要性.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗生素耐药性是一个日益增长的全球威胁,破坏了现代医学的进步.
- 不合理的抗生素使用加剧了这个问题,需要清楚地了解当前的处方模式.
研究的目的:
- 为了对巴基斯坦的抗生素处方做法进行基线差距分析.
- 确定在抗微生物药物管理方面需要改进的领域.
主要方法:
- 在巴基斯坦的六家公共部门三级医院进行了多中心,横截面的调查.
- 世界卫生组织 (WHO) 的点流行调查 (PPS) 方法用于收集2021年2月至3月的数据.
- 数据包括837名住院患者的医院基础设施,政策,实践,监测,反和患者特定的抗生素处方.
主要成果:
- 78.5%的受访住院患者被处方抗生素.
- 塞夫特里亚克松 (21.7%) 是最常被处方的抗生素,其次是美特罗尼达 (17.3%).
- 手术预防 (36.7%) 和社区感染 (24.7%) 是主要的指示. 显著的比例 (12.5%) 接受了三种或更多的抗生素,表明多药性.
结论:
- 这项研究显示,巴基斯坦医院的广泛抗菌药物消费量很高.
- 迫切需要扩大抗菌药物管理计划并实施有效的监测.
- 指导临床团队对于合理化抗生素使用和打击抗药性至关重要.
更多相关视频
19:57An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
18.6K
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
1.3K
相关概念视频
Prescription, Nonprescription and Orphan Drugs
761
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
761
Development of Antibiotic Resistance
36
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
36
Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Antimicrobial Effectiveness
43
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
43
Pharmacovigilance
884
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
884
Analysis of Population Pharmacokinetic Data
291
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
291
