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人类嘴唇的自身感应内化
José Martín-Cruces1, Patricia Cuendias1, Yolanda García-Mesa1
1Departamento de Morfología y Biología Celular, Grupo SINPOS, Universidad de Oviedo, Oviedo, Spain.
Anatomical record (Hoboken, N.J. : 2007)
|September 15, 2023
概括
人的嘴唇没有肌肉,但有密集的感觉神经形成,包括鲁菲尼式和帕奇尼式肉体. 这些神经末端,表达PIEZO2,可能使唇部自感.
科学领域:
- 神经科学是一个神经科学.
- 人体解剖学 解剖学 解剖学
- 感官生物学 感官生物学
背景情况:
- 面部肌肉,特别是口腔肌肉,传统上被认为没有像肌肉子这样的典型自受体.
- 最近的研究质疑了面部肌肉中缺少自身受体的存在,需要进一步调查.
研究的目的:
- 为了研究人类嘴唇的自身感应内化,专注于口腔肌肉.
- 为了确定肌肉的存在或不存在,并描述嘴唇中的其他感觉神经形成.
主要方法:
- 从冷尸体中使用人类唇部组织 (n=5).
- 进行了免疫组织化学检测S100蛋白 (神经),肌重链 (肌肉纤维) 和PIEZO2 (机械敏感通道).
主要成果:
- 在人类的嘴唇肌肉中没有发现典型的肌肉.
- 观察到高密度的形态上多样化的感觉神经形成.
- 这些形成表现出Ruffini-like和Pacinian粒体的特征.
- 这些感觉构成的轴突显示了PIEZO2免疫活性.
结论:
- 人的嘴唇肌肉没有典型的肌肉.
- 嘴唇配备了丰富的感官内接,可能是负责自觉的.
- 已识别的感觉神经形成,表达PIEZO2,在唇部感觉反中起着至关重要的作用.
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