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Updated: Jun 1, 2026

Protein Digestion, Ultrafiltration, and Size Exclusion Chromatography to Optimize the Isolation of Exosomes from Human Blood Plasma and Serum
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来自人体血的小细胞外囊泡的免疫捕获和蛋白质分析

Łukasz Skoczylas1, Marta Gawin1, Daniel Fochtman1,2

  • 1Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.

Proteomics
|September 15, 2023
PubMed
概括

细胞外囊泡 (EVs) 对于细胞通信至关重要,但由于异质性而难以分析. 免疫捕获提供了一种方法来隔离特定的EV子集用于蛋白质组分析.

关键词:
癌症生物标志物 癌症生物标志物高分辨率的质谱仪.免疫捕获 免疫捕获液体活检活检液体活检小小的细胞外囊泡.瘤衍生性SEV (TEX) 是一种由瘤衍生的SEV.

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Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
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NK cells are large granular lymphocytes found in the blood and lymphatic system. These...