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Updated: Jul 25, 2026

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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基于microRNA的组合疗法,通过非激活PI3K/Akt/mTOR通路来对抗TCI耐药性CML:一篇综述

Priyanka Singh1

  • 1Department of Biochemistry, School of Basic Sciences, Central University of Punjab, Ghudda, 151401, Bathinda, India. priyasingh2910@gmail.com.

Medical oncology (Northwood, London, England)
|September 15, 2023
PubMed
概括

这项研究确定了7种针对PI3K/Akt/mTOR途径的miRNA,为耐氨酸激酶抑制剂慢性髓性白血病 (CML) 提供了潜在的新疗法. 使用miRNAs和TKIs进行组合治疗可能会改善结果.

关键词:
在 BCR-ABL 基蛋白上.在白血病中,白血病.目标扫描 (TargetScan) 是一个扫描工具.dbDEMCC 的使用情况.在 miRBase 的基础上.

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