在引入产前心脏查后,妊娠终止和产后重大先天性心脏缺陷的患病率
Viktor Tomek1, Hana Jicínská2, Jan Pavlícek3
1Children's Heart Centre, Second Faculty of Medicine, Motol University Hospital, Charles University, Prague, the Czech Republic.
JAMA network open
|September 15, 2023
概括
产前查显著提高了先天性心脏缺陷 (CHD) 检测率,导致产后患病率下降. 然而,早期的第一季度查增加了CHD的终止率,但没有改变整体趋势.
科学领域:
- 心脏病学 心脏病学
- 产前诊断 在产前诊断
- 公共卫生 公共卫生
背景情况:
- 产前心脏查影响先天性心脏缺陷 (CHD) 患病率,妊娠终止和受影响儿童的结果.
- 了解心血管疾病检测和管理的趋势对于改善产前护理至关重要.
研究的目的:
- 分析31年来主要冠状动脉疾病的发病率,检测率和终止趋势.
- 评估产前心脏查和产后结果之间的关联.
主要方法:
- 在捷克共和国进行了一项为期31年的横截面研究 (1991-2021年).
- 通过使用国家登记册,对3827名被诊断为患有重大心血管疾病的胎儿和5454名患有重大心血管疾病的活生生的婴儿进行了分析.
主要成果:
- 主要心血管疾病的产前检测率从6.2%增加到82.8%.
- 大型冠状动脉疾病的产后患病率从0.21%降至0.14%.
- 第一个三个月的查 (2007年引入) 与第二个三个月的查 (42.6%) 相比,显示了更高的终止率 (73.3%).
结论:
- 主要冠状病的总发病率保持稳定,但由于产前检测和终止增加,产后患病率下降.
- 虽然第一季度查改善了早期检测,但它也提高了终止率,尽管CHD终止的整体趋势下降了.
- 产前查显著重塑了心血管疾病管理和结果的格局.
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