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基67和前列腺特异性抗原是转移性荷尔蒙原始前列腺癌的预后

Vasiliki Spyratou1, Eva Freyhult2, Anders Bergh3

  • 1Department of Urology, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.

Acta oncologica (Stockholm, Sweden)
|September 15, 2023
PubMed
概括

接受雄激素剥夺疗法 (ADT) 的前列腺癌患者可能从降级中受益. PSA 评分是最强的预后因素,超过 Ki67,这表明 PSA 评分可以识别那些仅仅对 ADT 反应良好的患者.

关键词:
转移性前列腺癌 转移性前列腺癌雄激素剥夺疗法是一种治疗方法.生物标志物生物标志物多塞塔克塞尔 (Docetaxel) 是一种药物.前列腺特异抗原前列腺特异抗原.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...