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一个分解蛋白和金属蛋白酶域9促进SARS-CoV-2进入具有低ACE2表达的细胞

Ivonne Melano1, Wei-Chung Cheng2,3, Li-Lan Kuo1

  • 1Graduate Institute of Biomedical Sciences, China Medical University , Taichung, Taiwan.

Microbiology spectrum
|September 15, 2023
PubMed
概括

一个分解蛋白和金属蛋白酶域9 (ADAM9) 作为SARS-CoV-2进入的关键宿主因子,通过与病毒Spike蛋白和ACE2相互作用来增强感染. 沉默ADAM9降低了传染性,即使对于有关变体,提供潜在的治疗点.

关键词:
这就是SARS-CoV-2病毒.冠状病毒冠状病毒病毒传染病是一种传染性疾病.病毒进入病毒的入口病毒与宿主之间的相互作用

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