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透到肺瘤的Treg具有与检查点阻塞反应相关的不同的转录形状和功能

Arbor G Dykema1,2,3, Jiajia Zhang1,2,3, Laurene S Cheung1,3

  • 1Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Science immunology
|September 15, 2023
PubMed
概括

调控性T细胞 (Treg) 子集在非小细胞肺癌的抗PD-1疗法中具有相反的作用. 虽然一些Treg抑制免疫力,但TAA特定的Treg可能会增强抗瘤反应.

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