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Updated: Jul 16, 2025

Observation and Quantification of Telomere and Repetitive Sequences Using Fluorescence In Situ Hybridization FISH with PNA Probes in Caenorhabditis elegans
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Observation and Quantification of Telomere and Repetitive Sequences Using Fluorescence In Situ Hybridization FISH with PNA Probes in Caenorhabditis elegans

Published on: August 4, 2016

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在Caenorhabditis elegans中,TERRA表达是由端粒结合蛋白POT-1和POT-2调节的

Caterina Manzato1, Luca Larini1, Claudio Oss Pegorar1

  • 1Laboratory of Cell Biology and Molecular Genetics, Department CIBIO, University of Trento, 38123, Trento, Italy.

Nucleic acids research
|September 15, 2023
PubMed
概括

在C. elegans中,端粒重复含有RNA (TERRA) 被POT蛋白调节,并表现出复杂的动态. 在端粒酶缺乏突变体中,TERRA被上调,揭示了对端粒维护的新见解.

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