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Updated: Jul 16, 2025

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
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不同的刺激会诱导内皮功能障碍,并通过Piezo1/YAP信号轴促进动脉样硬化

Jingying Mao1, Ronghao Yang2, Ping Yuan3

  • 1Department of Thyroid and Vascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China; Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.

Archives of biochemistry and biophysics
|September 15, 2023
PubMed
概括

在动脉样硬化模型中,Piezo1通道激活增加了自,并促进了血管内皮功能障碍. 这涉及到YES相关蛋白 (YAP) 信号的激活,突出了心血管疾病的潜在治疗点.

关键词:
动脉样硬化是一种动脉样硬化.自自是一种自的过程.这是一个Piezo1.剪切压力压力是什么哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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