血清度与狗的胰腺脂酶度相反相关
Harry Cridge1, Sichao Wang2, Joerg M Steiner3
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI.
American journal of veterinary research
|September 15, 2023
概括
电离 (iCa) 水平可能与狗的胰腺脂酶 (cPLI) 相反相关. 虽然原发性甲状腺功能障碍症 (PHPT) 病例中的高血可能与较高的cPLI有关,但本研究发现治疗后没有显著的变化.
科学领域:
- 兽医内科 兽医内科
- 狗内分泌学 狗内分泌学
- 生物化学 生物化学
背景情况:
- 胰腺脂酶 (cPLI) 和电离 (iCa) 是狗健康的关键生物标志物.
- 初级甲状腺功能增强症 (PHPT) 是一种以高血症为特征的疾病.
- 狗的iCa和cPLI之间的关系需要进一步研究.
研究的目的:
- 在狗中确定血清电离 (iCa) 和胰腺脂酶 (cPLI) 度之间的相关性.
- 评估治疗原发性偏甲状腺症 (PHPT) 的狗中超血症和cPLI度的缓解之间的关系.
主要方法:
- 分析了具有cPLI测试指示的狗的血清样本 (第一阶段) 和治疗前后PHPT的狗 (第二阶段).
- 电离和cPLI度分别使用光谱测量和Spec cPL测定进行测量.
- 斯皮尔曼的等级相关性和配对的t测试被用来分析数据.
主要成果:
- 在接受cPLI定量测定的狗中,血清iCa和cPLI度之间观察到负相关性 (r = -429,P = .005).
- 在PHPT犬中,cPLI度的中位数在高血症纠正前比PHPT犬的中位数更高,但这种差异在统计学上并不显著 (P = .70).
结论:
- 血清iCa和cPLI之间的反向关系可能存在于具有cPLI测试临床指示的狗身上,可能是由于耗.
- 一些狗的高血症可能与CPLI度高于参考区间相关.
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