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老年人的免疫疗法. 也许是肺癌的最佳选择?

Paul Zarogoulidis¹, Dimitris Matthaios², Panagoula Oikonomou³

¹Pulmonary Department, General Clinic Euromedica, Thessaloniki, Greece; 3rd University Surgery Department, ``AHEPA`` University Hospital, Thessaloniki, Greece.

Cancer treatment and research communications

|September 15, 2023

概括

新的支气管镜技术改善了肺癌的诊断,即使是在患有并发病的老年患者中也是如此. 免疫疗法和化疗免疫疗法似乎对老年人和非老年人群都安全,尽管需要进一步的研究.

科学领域:

肺部病理学肺部病理学
在瘤学瘤学.
医学诊断医学诊断医学诊断

背景情况:

肺癌通常在晚期被诊断出来,需要全身治疗.
最少侵入性支气管镜技术 (例如,机器人支气管镜,电磁导航) 提供高的诊断产量.
这些先进的技术可以进行分子研究,并且适用于患有COPD和心力衰竭等并发症的患者.

研究的目的:

审查目前用于肺癌诊断的最小侵入性支气管镜技术.
分析免疫治疗与化学免疫治疗在老年人和非老年肺癌患者的疗效和安全性.
讨论对患者分层和治疗选择的影响.

主要方法:

复习先进的支气管检查技术,包括凸内支气管超声波,辐射内支气管超声波,圆束CT,电磁导航和机器人支气管检查.
对现有研究进行分析,比较老年人 (≥75岁) 和非老年人 (≤74岁) 肺癌患者队列中的免疫疗法和化疗免疫疗法.
讨论诊断产量,样本适合分子测试,以及患者安全概况.

主要成果:

先进的支气管镜技术提供高的诊断产量与最小的不良影响,即使在患有并发症的患者.
老年人和非老年患者似乎可以同样容忍免疫疗法和化疗免疫疗法.
通过这些新的诊断方法,可以获得足够的样本进行分子检测.

结论:

最少侵入性支气管镜显著提高了肺癌诊断和分子分析能力.
目前的数据表明,免疫疗法和化疗免疫疗法的安全性和有效性在老年人和非老年肺癌患者中相似.
需要进行进一步的研究,以充分阐明不同患者亚组的最佳治疗策略和长期结果.

关键词:

不良影响不良影响活检是为了检查生物质.化疗化疗是一种化学疗法.圆束CT CT 圆束这是一辆EBUS的Ebus.年长的老人.非小细胞肺癌是非小细胞肺癌.辐射-e-bus 的使用.铁氨酸激酶抑制剂铁氨酸激酶抑制剂

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