使用Neuro-ICU患者多药耐药生物感染的风险预测模型:一个回顾性队列研究
Hu Jiang1, Hengping Pu1, Nanqu Huang2
1Nursing Department, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563000, Guizhou, China.
Scientific reports
|September 15, 2023
概括
多重耐药生物体 (MDRO) 感染在神经重症监护室 (ICU) 很常见. 关键的风险因素包括气管输管和肺炎,为更好的预防提供了新的预测模型.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
背景情况:
- 多重耐药生物体 (MDRO) 感染在重症监护机构中构成重大威胁.
- 神经重症监护室 (Neuro-ICU) 由于患者的敏性,特别容易受到伤害.
研究的目的:
- 确定神经ICU患者中MDRO感染的患病率和危险因素.
- 在这个人群中开发和验证MDRO感染风险预测模型.
主要方法:
- 对297名从神经急症监护室出院的患者 (2018年1月 - 2020年4月) 的回顾性分析.
- 二元物流回归确定了风险因素.
- 接收器操作特征 (ROC) 曲线分析验证了预测模型 (AUC=0.887).
主要成果:
- MDRO感染率为44.11% (131/297名患者).
- 确定了独立的危险因素:气管输管,动脉血压监测,发烧,抗生素使用和肺炎 (P < 0.05).
- 预测模型显示了高灵敏度 (86.3%) 和特异性 (76.9%).
结论:
- 显著比例的神经-ICU患者获得MDRO感染.
- 开发的风险预测模型有效地识别了患有MDRO感染高风险的患者.
- 结果可以指导针对性的预防策略和护理干预在Neuro-ICUs.
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