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用扩散张力图像来探索贝尔的病变发生.

Yi Qin1,2, Jihua Liu3,4, Xuening Zhang5

  • 1Radiology Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, No. 88, ChangLing Road, XiQing District, Tianjin, 300381, China.

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概括

扩散张力成像显示,面部内神经内髓损伤导致贝尔. 这一发现表明大多数神经轴突仍然完好无损,解释了这种情况的典型自我限制性质.

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科学领域:

  • 神经成像是一种神经成像.
  • 神经学 神经学
  • 医疗成像医学成像

背景情况:

  • 贝尔是一种常见的神经疾病,影响面部神经功能.
  • 贝尔麻的确切病变发生,特别是神经损伤的程度,仍然不完全理解.

研究的目的:

  • 在3.0特斯拉磁共振 (MR) 扫描仪上使用扩散张力成像 (DTI) 调查贝尔的病变发生.
  • 为了区分骨髓膜损伤和轴突损伤在贝尔的面部神经内侧神经的患者.

主要方法:

  • 在健康人群和贝尔患者中获得了DTI和T1结构序列.
  • 通过使用DTI数据跟踪内面部神经,这些数据是使用TrackVis及其扩散工具包处理的.
  • 扩散参数,包括分数异构 (FA),平均扩散率 (MD),轴向扩散率 (AD) 和辐射扩散率 (RD),用于神经通道计算.

主要成果:

  • 健康个体在双边面部神经之间在FA,MD,RD和AD中没有显著差异.
  • 贝尔患者在受影响和健康的面部神经之间在FA,MD和RD中表现出显著的差异 (P <0.02).
  • 在贝尔麻患者中,受影响的神经和健康的神经之间没有观察到AD的显著差异.

结论:

  • 面部内神经的髓膜损伤是贝尔的主要原因.
  • 在大多数贝尔麻病例中,轴突的完整性在很大程度上被保留.
  • 这些发现支持在大多数贝尔麻病例中观察到的自我限制性质.