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移植后的切口:一个系统的审查和元分析
B M Mac Curtain1,2, W Qian3, H C Temperley4
1School of Medicine, University of Galway, Galway, Ireland. b.maccurtain1@nuigalway.ie.
Hernia : the journal of hernias and abdominal wall surgery
|September 15, 2023
概括
移植后的切口是不常见的,发生在4%的患者中. 大多数需要进行手术修复,在术后观察到的复发率为16%.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 手术瘤学手术瘤学
- 移植手术 移植手术
背景情况:
- 移植 (RT) 后的切口 (IH) 由于移植和患者免疫抑制,提出了独特的临床挑战.
- 了解IH发生率,风险因素和结果对于移植后患者管理至关重要.
研究的目的:
- 系统地审查和对移植后切口率的现有文献进行元分析.
- 确定与RT后IH发展相关的关键风险因素.
- 评估结局,包括移植受体中IH的修复率和复发率.
主要方法:
- 在PubMed,EMBASE和Cochrane CENTRAL进行了全面的文献搜索,截至2023年7月.
- 按照PRISMA指南进行了系统审查和元分析.
- 计算了IH发生率,修复率和复发率的聚合比例.
主要成果:
- 该分析包括了20项研究,涉及16,018名患者.
- 综合的IH后RT发病率为4% (CI为3-5%).
- 整体IH修复率为61% (CI 14-100%),修复后复发率为16% (CI 9-23%).
- 确定的危险因素包括BMI,免疫抑制,年龄,吸烟,切口类型,重新手术,并发腹壁,淋巴细胞和肺部疾病.
结论:
- 切口是一个不常见的移植后的并发症.
- 大多数被发现的切口的治疗方法是选择性手术修复.
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