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哪些糖尿病患者使用一次性半单位胰岛素笔进行治疗? 在西班牙的真实世界,回顾性,数据库研究
F Javier Ampudia-Blasco1, Natalia Duque2, Esther Artime2
1Endocrinology and Nutrition Department, Clinic University Hospital Valencia, INCLIVA Research Foundation, Valencia, Spain.
Jr KwikPen是一款半单位的胰岛素笔,在西班牙被一群多样化的糖尿病患者使用. 这项现实研究表明,它在各种年龄组和疾病中处方,包括1型和2型糖尿病.
科学领域:
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
- 现实世界的证据研究研究.
背景情况:
- 胰岛素lispro 100单位/毫升 Jr KwikPen 提供精确的0.5单位剂量用于糖尿病管理.
- 了解启动这种治疗的真实世界患者概况对于优化糖尿病护理至关重要.
研究的目的:
- 描述在西班牙使用Jr KwikPen开始胰岛素治疗的患者的社会人口统计和临床特征.
- 在现实环境中使用Jr KwikPen分析1型 (T1D) 和2型 (T2D) 糖尿病患者的个人资料.
主要方法:
- 使用IQVIA电子医疗记录数据库进行了回顾性观察性研究.
- 包括在2018年5月至2020年12月期间开始Jr KwikPen治疗的T1D或T2D患者.
- 在治疗开始时对社会人口统计学,临床和治疗特征进行描述性分析.
主要成果:
- 总共包括416名患者 (326名T1D,90名T2D),年龄范围广泛,体重指数不同.
- 患者血糖控制不足 (HbA1c 7.8%-8.0%) 和显著的并发症,特别是在T2D组 (64.4%).
- Jr KwikPen被处方给各种人群,包括儿科患者 (<18岁),老年人 (≥65岁),新诊断的患者和孕妇.
结论:
- 在现实实践中,启动Jr KwikPen治疗的患者概况是多样化的,包括各种年龄组和糖尿病类型.
- 大多数患者的血糖控制不充分,并出现相关的并发症,这表明需要精确的胰岛素定位.
- 研究结果表明,Jr KwikPen适用于需要更细致的胰岛素剂量调整的患者,包括儿童,青少年,成年人,老年人和孕妇.
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