大脑动脉瘤在不同年龄段的形态特征
Sebastian Sanchez1, Muhammed Amir Essibayi2, Meredith Hickerson1
1Department of Neurology, University of Iowa, USA.
概括
脑动脉瘤破裂的风险因年龄而异. 年轻患者的动脉瘤较小,通常位于MCA/ACOM,而老年患者的动脉瘤更大,更不规则,通常在PCOM/ACOM. 不规则性会增加所有年龄段的破裂风险.
科学领域:
- 神经学 神经学
- 血管外科 血管外科
- 放射学 放射学是一门学科.
背景情况:
- 患者的年龄是动脉瘤破裂风险的一个关键因素.
- 关于脑动脉瘤形态的年龄相关差异的数据有限.
- 这项研究调查了不同年龄组脑动脉瘤的形态变异.
研究的目的:
- 分析脑动脉瘤与患者年龄相关的形态特征.
- 为了确定动脉瘤位置,大小和形状的特定年龄模式.
- 评估形态和年龄对动脉瘤破裂风险的影响.
主要方法:
- 从中风血栓切除和动脉瘤注册 (STAR) 中分析了1407个未破裂的和607个破裂的囊性动脉瘤.
- 评估动脉瘤参数,包括位置,大小,部尺寸,面积比和形态 (正规与不规则).
- 用于估计破裂风险呈现的物流回归.
主要成果:
- 动脉瘤的大小随着年龄的增长而增加,未破裂的病例 (p < .001),但破裂的病例没有 (p = .142).
- 破裂动脉瘤的位置因年龄不同:年轻 (<70) 患者的MCA/ACOM与老年 (>70) 患者的PCOM/ACOM.
- 无论是未破裂的动脉瘤还是破裂的动脉瘤,随着年龄的增长,不规则性都增加了 (分别p < .001和p = .025).
结论:
- 较年轻的患者 (<70) 呈现较小的动脉瘤,主要在MCA/ACOM中,破裂风险受位置和不规则性的影响.
- 老年患者 (>70) 呈现较大,更不规则的未破裂动脉瘤,在PCOM/ACOM中经常出现破裂动脉瘤.
- 不规则的动脉瘤形态是所有年龄人口统计数据中破裂的重要危险因素.
相关概念视频
Aneurysm I: Introduction
12
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
12
Aneurysm III: Interprofessional Care
9
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
9
Aneurysm II: Clinical Manifestations and Diagnostic Studies
10
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Anatomy of the Brain: Ventricles
4.2K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
4.2K
The Arch of Aorta
732
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
732
Arteries of the Head and Neck
1.4K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.4K


