流行病的乳头细胞膜纤维瘤:一个病例报告
Xenia Parisi1, Alexander Feinstein2, Yekaterina Merkulova1
1Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
International journal of surgical pathology
|September 16, 2023
概括
本报告详细介绍了第二个已知的流行性囊腺纤维瘤病例,这是男性罕见的阴囊质块. 组织病理学和免疫组织化学表明,这种不寻常的瘤可能起源于沃尔夫管道.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 病理学 病理学 病理学
- 生殖医学 生殖医学
背景情况:
- 胸膜囊膜瘤是一种极其罕见的瘤,在英语文献中仅记录了一例先前的病例.
- 这项研究是第二次报告这种罕见疾病的案例.
研究的目的:
- 在54岁的男性患者中报告了第二例 epididymal cystadenofibroma.
- 分析瘤的组织病理学和免疫组织化学特征.
- 讨论瘤的潜在起源,考虑到其独特的树皮和上皮特征.
主要方法:
- 一个54岁的男性患有阴囊质量的案例介绍.
- 粗略检查6.3厘米的阴囊质量.
- 显微镜检查树皮和上皮组成部分.
- 对于雌激素受体,孕激素受体,CD10,角质尾酒AE1/3&CAM5.2,PAX8,雄激素受体和α-1抗素的免疫组合化学染色.
主要成果:
- 阴囊质量测量6.3厘米,含有囊性病变,内部乳头充满了血清到凝液.
- 在显微镜上,瘤显示出状状细胞和立方形到柱状/状上皮质.
- 免疫组织化学检查显示了卵巢类型的肌层 (ER,PR,CD10阳性) 和上皮 (CK AE1/3&CAM5.2,CD10,PAX8,AR,A1AT阳性).
结论:
- 第二个报告的流行性囊腺纤维瘤病例突出了其极其罕见的情况.
- 免疫组织化学特征,特别是卵巢类型的肌层和特定的上皮标记,表明这种瘤可能起源于沃尔夫管道.
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