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通过动态S-化来调节ERK2活动

Saara-Anne Azizi1, Tian Qiu2, Noah E Brookes2

  • 1Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Medical Scientist Training Program, Pritzker School of Medicine, The University of Chicago, Chicago, IL 60637, USA.

Cell reports
|September 16, 2023
PubMed
概括

细胞外信号调节激酶 (ERK1/2) 通过S-化,一种可逆的脂质修饰,获得新的调节层. 这种脂化影响ERK1/2信号传递,与代谢综合征有关,提供了新的治疗点.

关键词:
科普:分子生物学 分子生物学化学生物学 化学生物学激酶信号传递中的激酶信号.脂肪化 脂化 脂化

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