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在多发性硬化症患者的定量敏感度映射 (QSM) 上对偏磁边缘损伤分类的可靠性:单位经验和系统审查

Jack A Reeves¹, Maryam Mohebbi¹, Robert Zivadinov²

¹Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High Street, Buffalo, NY 14203, USA.

Multiple sclerosis and related disorders

|September 16, 2023

概括

在多发性硬化症 (MS) 中,通过使用定量敏感度映射 (QSM) 可靠地检测出偏磁边缘病变 (PRL). 这项研究证实了PRL评估的高inter-rater和intra-rater可靠性,这对其诊断潜力至关重要.

科学领域:

神经成像是一种神经成像.
放射学放射学是一门学科.
神经学神经学

背景情况:

对铁敏感的MRI技术可视化慢性活性病变在体内作为偏磁边缘病变 (PRLs).
偏磁边缘病变 (PRLs) 显示出对多发性硬化症 (MS) 的诊断和预后工具的潜力.
有限的研究报告了PRL评估的可靠性,需要进一步评估.

结论:

偏磁边缘病变 (PRLs) 可以在每病变和每个患者的水平上可靠地检测到.
未来的PRL研究应该报告详细的可靠性结果,包括评价者的经验.
建议使用标准化的可靠性指标 (科恩 κ 或 ICC) 来提高研究可比性.

关键词:

3T 3T 3T 3T 3T 3T 3T 3T 3T 3T 3T 3T 长期活跃的病变慢性活跃的病变铁轮圈损伤铁轮圈损伤铁轮圈损伤多发性硬化症是多发性硬化症.偏磁边缘损伤偏磁边缘损伤定量敏感性映射测绘定量敏感性映射测绘可靠性可靠性可靠性

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Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...