在家进行运动可以改善多发性硬化症中亚临床动脉样硬化标志物
Tracy Baynard1, Garett J Griffith2, Sang Ouk Wee3
1Integrative Physiology Laboratory, University of Illinois at Chicago, Chicago, IL 60612; Currently affiliated with the Manning College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA 02125.
Multiple sclerosis and related disorders
|September 16, 2023
概括
在家进行有氧运动显著改善了多发性硬化症 (MS) 患者的有氧能力,步行速度和血管功能. 这种为期12周的干预措施提供了一种可行的策略,可以提高MS患者的健康状况并减少动脉样硬化标志物.
科学领域:
- 神经学 神经学
- 运动生理学 运动生理学
- 心血管科学 心血管科学
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病,影响有氧健身和运动能力.
- 亚临床动脉样硬化对MS患者构成重大风险.
- 需要基于家庭的干预措施来改善MS的健康结果.
研究的目的:
- 评估一项为期12周的家庭有氧训练计划对多发性硬化症患者的有氧健身,亚临床动脉样硬化和运动能力的影响.
- 为了比较有氧运动对注意力控制组的影响.
主要方法:
- 一项为期12周的随机对照试验,涉及多发性硬化症患者 (扩展残疾状况尺度0-4).
- 参与者被分配到有氧运动 (n=26) 或注意力控制伸展组 (n=22).
- 测量了有氧容量,动脉内膜介质厚度,血管扩展反应能力,动脉硬度和运动能力 (定时25英尺步行测试,6分钟步行测试). 社会认知理论行为辅导被利用.
主要成果:
- 有氧运动组的有氧能力 (7%),血管扩展反应 (16%) 和定时25英尺步行测试速度 (13%) 显著改善.
- 在注意力控制组中没有观察到显著的变化.
- 这些改善表明运动对心血管健康标志物的积极影响.
结论:
- 12周的家庭有氧运动干预可以导致MS患者的有氧能力,流动性和血管功能中适度但显著的改善.
- 这种干预表明了改善亚临床动脉样硬化标志物的潜力.
- 需要进一步的研究来调查这些结果在预先选心血管相关疾病和移动性问题的人群中.
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