在牛中营养先天性肠病变的特征
Luis A Colque-Caro1, Francisco Acuña2, Laura S Aguirre1
1Área de Sanidad Animal "Dr. Bernardo Jorge Carrillo" Instituto de Investigación Animal Chaco Semiárido, CIAP, Instituto Nacional de Tecnología Agropecuaria (INTA), Ruta Nac. 68 - Km 172, Salta, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) CCT SALTA - JUJUY, Rivadavia 941, Salta, Argentina.
这项研究特征牛,发现甲状腺体重相对于体重和细胞增殖增加的严重程度. 这些形态测量和免疫组织化学变化与母亲的甲状腺激素水平和状态有关.
科学领域:
- 兽医病理学 兽医病理学
- 内分泌学 在内分泌学.
- 比较解剖学的比较解剖学
背景情况:
- 牛没有详细的形态测量和免疫组织化学特征.
- 母亲的甲状腺激素水平和补充剂会影响胎儿的发育.
研究的目的:
- 为了分类和描述牛甲状腺喉的形态学和免疫组织化学特征.
- 为了将这些特征与母因子和本病理学分级相关联.
主要方法:
- 研究了来自胎儿,死胎和新生儿的49种牛甲状腺.
- 评估体重,甲状腺体重,并计算甲状腺体重与体重的比率.
- 进行了组织病理学分类 (G0-G3) 和用于增殖细胞核抗原 (PCNA) 的免疫组织化学.
主要成果:
- 甲状腺体重与体重比的显著差异在全身病理学等级 (P <0.05) 中观察到.
- 甲状腺毛囊细胞高度,上皮高度和PCNA免疫标记随着的严重程度增加 (P < 0.001).
- 甲状腺体重与体重的比率与组织学等级正相关 (P = 0.008).
结论:
- 甲状腺体重与体重的比率和PCNA表达是牛的严重程度的可靠指标.
- 这些发现凸显了母亲和甲状腺激素状态对牛甲状腺发育的影响.
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