患有的成年人中维生素D缺乏的患病率和预测因素:一个横截面研究
Ching Soong Khoo1, Mohd Fadzli Shukor2, Juen Kiem Tan1
1Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia.
维生素D缺乏症在患者中很常见,影响了近一半的研究对象. 年龄,性别和种族等因素与这种缺陷有关,突出显示了查的必要性.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 在患者 (PWE) 中,维生素D缺乏的研究不足.
- 维生素D对于骨健康和恒温至关重要.
- 相关的因素可能会影响维生素D的代谢.
研究的目的:
- 调查多民族成年患者群体中维生素D缺乏的患病率.
- 在患者中确定与维生素D缺乏相关的因素.
主要方法:
- 一个单一中心的横截面研究,对159名患有的成年人进行了抗发作药物 (ASM) 治疗.
- 排除患有影响维生素D代谢的疾病的患者.
- 对血清25-氧维生素D3 [25(OH) D],蛋白校正,酸盐和性酸酶的分析.
主要成果:
- 45.9%的参与者缺乏维生素D,23.9%的参与者缺乏维生素D,30.2%的参与者有足够的维生素D水平.
- 缺乏的预测因素包括年龄较小 (18-44岁),女性性别和特定的种族 (马来人,中国人).
- 在ASM,血清和维生素D缺乏之间没有发现显著的关联.
结论:
- 维生素D缺乏症在患有的人群中很普遍.
- 建议在高危人群中定期查维生素D缺乏症.
- 早期识别和干预可以预防未来的并发症.
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