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Updated: Jul 16, 2025

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy
11:22

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Published on: June 27, 2018

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在亨廷顿病的敲门猪中突变的亨廷丁蛋白异常拼接

Huichun Tong1, Tianqi Yang1, Li Liu1

  • 1Guangdong Key Laboratory of Non-human Primate Research, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China.

Neurobiology of disease
|September 16, 2023
PubMed
概括

异常拼接的亨廷丁基因 (HTT) exon1 在亨廷顿病 (HD) 猪大脑中存在,但水平非常低. 这表明它对疾病发病的贡献可能不如以前想象的那么重要.

关键词:
这是一种异常的拼接.Htt N-终端碎片的部分这里是exon1碎片.亨廷顿病,HD KI猪猪的疾病.

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