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Updated: Jul 16, 2025

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纤维细胞中的积分素缺乏会影响中间纤维和器官的形态,迁移和粘附

Michaela M Zrelski1, Sabrina Hösele1, Monika Kustermann1

  • 1Department of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.

The Journal of investigative dermatology
|September 16, 2023
PubMed
概括

肌肉发育不良 (EBS-MD) 的表皮溶解牛简单体中的积蛋白缺乏会损害纤维细胞的功能,导致细胞异常和减少伤口愈合. 这项研究揭示了这种遗传性皮肤疾病背后的关键机制.

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