脚关节:脚关节炎的非手术更新,生物疗法是否有效?
Kyle S Peterson1, Vincent Vacketta2, Amber Kavanagh3
1Suburban Orthopaedics, 1110 West Schick Road, Bartlett, IL 60103, USA.
Clinics in podiatric medicine and surgery
|September 16, 2023
概括
大多数脚关节炎都源于受伤,导致疼痛和硬. 先进的成像和注射 (皮质类固醇,PRP) 等治疗方法可以控制症状并减缓软骨损伤.
科学领域:
- 整形外科 整形外科 整形外科
- 运动医学 运动医学
- 再生医学是一种再生医学.
背景情况:
- 脚关节炎主要是由创伤造成的 (60-80%)
- 关键症状包括疼痛,运动能力下降和胀.
- 准确的诊断依赖于先进的成像技术,如MRI和CT扫描.
研究的目的:
- 审查当前对创伤后脚关节炎的理解.
- 探索诊断成像技术的使用.
- 要总结保守和新兴的注射治疗选择.
主要方法:
- 关于创伤后脚关节炎的文献综述
- 诊断成像敏感性的分析 (MRI,CT)
- 对注射疗法 (皮质类固醇,酸,PRP,羊水产品) 的评估.
主要成果:
- 创伤后病因是关节关节炎的主要原因.
- 像MRI和CT这样的成像模式对于评估退化至关重要.
- 可注射疗法提供抗炎和软骨保护的好处.
结论:
- 有效的管理涉及症状减少和功能改善.
- 注射治疗,包括生物药物,越来越重要.
- 这些疗法旨在减少炎症并防止进一步的软骨分解.
相关概念视频
Ankle Joint
1.6K
The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
1.6K
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
168
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
168


