智能和多功能生物材料用于皮肤伤口愈合
Minxiong Li1, Wenzheng Xia1, Yi Min Khoong1
1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Biomaterials research
|September 16, 2023
概括
智能伤口带为治疗皮肤伤口提供了先进的解决方案,解决了传统治疗方法的局限性. 本综述探讨了响应性材料,它们的机制,以及改善伤口护理的临床潜力.
科学领域:
- 生物材料科学 生物材料科学
- 伤口治愈研究研究 伤口治愈研究
- 智能材料是一种智能材料.
背景情况:
- 皮肤伤口给全球健康和经济带来了重大挑战.
- 传统的伤口带在解决复杂的伤口愈合过程方面存在局限性.
- 智能伤口包裹正在成为有前途的治疗平台.
研究的目的:
- 审查伤口愈合过程和现有的生物材料.
- 总结用于伤口愈合的智能响应材料的机制.
- 讨论智能伤口带的最新进展,临床进展,挑战和未来前景.
主要方法:
- 关于伤口愈合过程和生物材料的文献综述.
- 对智能响应材料机制的分析.
- 在皮肤伤口愈合的智能材料的最新进展的综合.
- 讨论临床转化和未来前景.
主要成果:
- 关于伤口愈合和当前生物材料的详细概述.
- 解释各种智能响应材料机制.
- 突出显示创伤应用的新型智能和多功能材料.
- 评估临床进展和发现的挑战.
结论:
- 智能响应材料为皮肤伤口愈合提供了量身定制的解决方案.
- 了解材料组成和响应机制是设计有效的智能包裹的关键.
- 进一步的研究和临床翻译对于推进智能伤口包裹技术至关重要.
相关概念视频
01:19Clinical Applications of Epidermal Stem Cells
2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
01:28Phases of Wound Repair
6.1K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
6.1K