功能神经和偏头痛:一个系统的审查和病例系列
Laura Duque1, Ivan Garza2, Gregory D Cascino3
1Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Epilepsy & behavior : E&B
|September 17, 2023
概括
偏头痛发作可能引发功能神经障碍 (FND) 发作. 偏头痛预防药物可以减少FND发作和头痛频率,需要进一步调查.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 神经学 神经学
背景情况:
- 功能神经障碍与 (FND-) 是一种常见的神经精神疾病,通常与心理压力因素有关,但神经障碍也可能是触发因素.
- 早期观察发现FND症状与偏头痛之间存在联系,但这种关系仍未得到充分探索.
- 这项研究调查了FND发作和偏头痛之间的关联,以及偏头痛预防在治疗FND发作中的有效性.
研究的目的:
- 系统地审查有关FND发作和偏头痛之间的关联的现有文献.
- 评估偏头痛预防药物在治疗FND发作中的有效性.
- 对患有FND和偏头痛的患者进行回顾性分析,评估治疗反应.
主要方法:
- 使用PRISMA指南进行了系统审查,搜索EMBASE和Scopus数据库,截至2021年3月31日.
- 一个多学科团队分析了连续诊断为FND和偏头痛的患者.
- 评估了潜在的因果关系和对标准偏头痛预防治疗的反应.
主要成果:
- 系统性审查确定了七项涉及1,186名患者的研究,所有这些研究都表明FND发作与偏头痛之间存在关联.
- FND发作和偏头痛之间的关联比发作和偏头痛之间的关联更强.
- 在一系列回顾的病例中,偏头痛发作在65.1%的患者中引发了FND发作;偏头痛预防在73%的患者中减少了超过50%的发作和头痛频率.
结论:
- 偏头痛发作可能会比以前认为的更频繁地引发FND发作.
- 偏头痛预防药物在减少FND发作频率方面表现有前途.
- 需要进一步的前性研究来证实这些发现.
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