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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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通过口服途径使用基于Poly (δ-decalactone) 的纳米乳液减轻塞莱科西布心脏毒性

Saurabh Maru1, Jyoti Verma2, Carl-Eric Wilen3

  • 1School of Pharmacy and Technology Management, SVKM's NMIMS, Babulde, Banks of Tapi River, Mumbai-Agra Road, Shirpur, Maharashtra 425405, India.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|September 17, 2023
PubMed
概括

这项研究开发了一种纳米乳液 (NE) 用于切莱科西布 (CLX),改善溶解度并降低心脏毒性. 聚甲 (δ-decalactone) NE增强了不易溶解药物的抗炎活性和生物利用性.

关键词:
它具有抗炎活性,具有抗炎活性.对心脏有毒性的心脏毒性这是一种纳米乳液.纳米沉是一种纳米沉.药理动力学, 口服输送, 口服输送

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