编辑的选择 - - IIIb型内皮膜:新一代内膜假肢的织物穿孔
Damir Vakhitov1, Jonathan Grandhomme2, Salomé Kuntz2
1GEPROMED, Strasbourg, France.
概括
扩张内移植 (EGs) 中的组织降解可能导致IIIb型内泄. 支架相关的穿孔,受植入时间和移植形状的影响,是最大和最关心的织物缺陷.
科学领域:
- 生物材料科学是生物材料的科学.
- 这是血管外科手术.
- 医疗器械分析 医疗器械分析
背景情况:
- 内脏移植 (EG) 对于治疗大动脉动脉瘤至关重要.
- 织物降解和内脏泄漏仍然是一个重大问题.
- 了解已解释的设备故障对于改进未来设计至关重要.
研究的目的:
- 为了分析探索的内脏移植 (EGs).
- 识别和描述织物降解机制.
- 为了将织物缺陷与IIIb型内脏漏洞相关联.
主要方法:
- 分析了32个具有宏观织物缺陷的EXPLANTED EG.
- 按照ISO 9001标准进行显微镜检查 (20-200倍放大).
- 压力测试,以评估潜在的穿孔机制.
主要成果:
- 在46%的探索者中发现了388个织物穿孔.
- 扩展聚四乙烯 (ePTFE) 疲劳和聚乙烯四甲酸盐 (PET) 扭曲是常见的降解模式.
- 与支架相关的穿孔更大,并且与更宽的支架间空间和更长的植入时间有关.
结论:
- 内移植组织的退化会导致穿孔,增加内脏泄漏的风险.
- 与支架相关的穿孔是最大的,受植入时间和移植形状的影响.
- 调查结果强调需要改进EG设计和材料耐用性.
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