患有慢性脏疾病的患者中与不接种流感疫苗相关的因素:慢性脏功能缺陷队列研究 (CRIC) 的发现
Junichi Ishigami1, Bernard G Jaar2, Jeanne B Charleston3
1Department of Epidemiology, Bloomberg School of Public Health, School of Medicine, Johns Hopkins University, Baltimore, Maryland; Welch Center for Prevention, Epidemiology, and Clinical Research, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
概括
对于患有慢性病 (CKD) 的人来说,接种流感疫苗至关重要. 年龄较小,黑人种族和健康的社会决定因素与这一群体的疫苗接种率较低有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 免疫学 免疫学 免疫学
背景情况:
- 推给患有慢性病 (CKD) 的患者进行流感疫苗接种,因为他们的免疫力受损.
- 在这个高风险群体中识别流感疫苗接种障碍对于公共卫生战略至关重要.
研究的目的:
- 确定与患有慢性瘤的成年人中流感未接种疫苗相关的人口,社会,临床和行为风险因素.
- 为改善流感疫苗在CKD群体中的接种提供信息的有针对性的干预措施.
主要方法:
- 这是一项对3692名参与慢性功能缺陷队列研究 (CRIC) 的纵向观察性研究.
- 混合效应的Poisson模型被用来估计调整的流感不接种疫苗的流行率 (APR).
- 分析了人口统计数据,健康的社会决定因素,临床条件和健康行为.
主要成果:
- 在2009年至2020年期间,流感疫苗接种率的综合平均值为72%.
- 与未接种疫苗相关的因素包括年龄较小,黑人种族,教育和收入较低,以前的婚姻状况和失业.
- 相反,糖尿病,COPD,末期脏病,虚弱和理想的身体活动与更高的疫苗接种率有关.
结论:
- 年轻的成年人,黑人,以及那些有不良健康社会决定因素的人更有可能没有接种流感疫苗.
- 需要有针对性的策略来解决差异,并减少成年CKD患者流感疫苗接种障碍.
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