初级皮肤无腺癌,在管状无腺瘤中产生
MacKenzie Griffith1, Raj Singh1, Anas Alabkaa2
1Rush Medical College, Chicago, Illinois, USA.
Journal of cutaneous pathology
|September 18, 2023
概括
初级皮肤无腺癌是一种罕见的部瘤,可以在良性病变中出现. 早期诊断和治疗对于这些不常见的副瘤的良好结果至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 初级皮肤无腺癌是一种罕见的恶性瘤,起源于无腺.
- 这些瘤可能与良性阿波克林增生症有关,使诊断复杂化.
- 长期的病变史并不排除恶性瘤.
研究的目的:
- 在良性阿波克林腺瘤中引起的原发性皮肤阿波克林癌症病例报告.
- 为了强调部病变的诊断考量与混合本位病理学.
- 为了展示这种罕见瘤的成功管理和随访.
主要方法:
- 一个70岁的女性的病例介绍,她有3年的无症状部病变史.
- 切除活检用于组织病理学检查.
- 免疫组织化学分析,以确认诊断.
- 随后进行广泛的局部切除和哨兵节点活检.
主要成果:
- 组织病理学揭示了一种双相瘤:一种良性管状阿波克林腺瘤组成部分和一种恶性阿波克林癌细胞组成部分.
- 脊髓癌的诊断得到了他的病理学特征和免疫组织化学的支持.
- 患者在手术后12个月保持无疾病,没有复发.
结论:
- 初级皮肤无腺癌可以在先前存在的良性无腺瘤中出现.
- 长期存在的 Vulvar 病变需要对恶性瘤进行彻底评估.
- 包括广泛局部切除和哨兵节点活检在内的手术管理对于这种罕见的癌症可能是有效的.
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