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基于模型的精确剂量定量,以快速达到度-时间曲线下的目标区域:模拟研究

Kazutaka Oda1,2, Tomoyuki Yamada3, Kazuaki Matsumoto4

  • 1Department of Pharmacy, Kumamoto University Hospital, Kumamoto, Japan.

Clinical and translational science
|September 18, 2023
PubMed
概括

有限的采样策略改善了范科米辛治疗药物监测. 第一天的低谷和高峰度提高了实现曲线下的面积 (AUC) 目标的速度,特别是AUC0-24和AUC24-48.

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