增加临床非血冷时间符合质量规格
Kelly M Winter1, Rachel G Webb1, Eugenia Mazur1
1Research and Development, Australian Red Cross Lifeblood, Alexandria, New South Wales, Australia.
Vox sanguinis
|September 18, 2023
概括
临床非性血质量在收集后12小时内冷时保持稳定. 这一发现支持延长冷时间,改善地理上具有挑战性的地区的血液供应物流.
科学领域:
- 血液银行和输血医疗
- 临床病理学 临床病理学
- 凝血的生物化学 凝血的生物化学
背景情况:
- 澳大利亚的地理挑战影响了血液供应物流.
- 延长临床血冷时间对于供应链效率至关重要.
研究的目的:
- 为了评估临床非血的质量.
- 为了确定12小时内冷的血是否符合临床规格.
主要方法:
- 聚合血样本 (n=20) 被收集并储存在26°C.
- 样品在采集后6小时,8小时和12小时进行了无菌检测.
- 凝血因子 (II,V,VII,VIII,XIII),·维勒布兰德因子和纤维素原被量化.
主要成果:
- 第八因子 (FVIII) 度显示非显著下降 (p=0.3338),但仍然高于0.7 IU/mL的临床规格.
- 纤维素和·维勒布兰德因子 (vWF) 度保持稳定.
- 凝血因子II,V,VII和XIII没有显著变化 (p>0.05).
结论:
- 临床非性血质量在收集后12小时内冷时保持不变.
- 这种延长的时间框架可以通过从偏远的捐献中心收集血液来提高血液供应.
- 这些发现支持修订的等离子处理协议,以提高供应链的灵活性.
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