在早产婴儿中意外过量服用脂质:一个病例报告
M S Ryan1, J McIntyre2, L D Bramwell3
1Centre for Perinatal Research, Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, UK.
Journal of neonatal-perinatal medicine
|September 18, 2023
概括
在早产婴儿中,静脉注射脂类乳液 (ILEs) 的意外过量服用并没有导致明显的伤害. 这一案例强调了报告新生儿药物错误的不同结果的重要性,以告知临床实践并减少父母的痛苦.
科学领域:
- 新生儿医学 新生儿医学
- 临床药房 临床药房
- 儿童营养学 儿童营养学
背景情况:
- 静脉输入的脂质乳液 (ILEs) 对于在腹腔营养 (PN) 期间提供必需脂肪酸至关重要.
- 过量服用ILE可能导致严重的不良事件,包括死亡率.
- 意外的药物错误,如ILE过量服用,在新生儿护理中构成重大风险.
研究的目的:
- 报告在早产婴儿中意外过量服用ILE的病例.
- 讨论显著的ILE过量后的临床结果.
- 强调报告新生儿药物错误的全部结果的重要性.
主要方法:
- 一个29周妊娠年龄的早产婴儿在50分钟内接受了大约三倍的每日推剂量20%的内脂.
- 给药后对临床状态和实验室样本进行了监测.
- 长期神经发育结果在经过2年纠正的妊娠年龄后进行评估.
主要成果:
- 婴儿没有明显的临床恶化,尽管脂质血液样本.
- 经过妊娠年龄调整后2年的神经发育结果与婴儿双胞胎的结果相似.
- 在输液包装和给药方案中实施了服务变化,以防止未来的错误.
结论:
- 新生儿护理中的药物错误是一个常见的现象.
- 仅报告药物错误的严重结果可能会给父母带来不必要的痛苦.
- 提供全方位的结果,包括避免伤害的情况,为医疗保健专业人员和家庭提供了宝贵的经验教训.
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