报告给美国中毒中心的儿童多动症治疗错误,2000年至2021年
Mikaela M DeCoster1,2, Henry A Spiller3,4, Jaahnavi Badeti1
1Center for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
涉及青少年注意力缺陷/多动症 (ADHD) 药物治疗的医院外治疗错误从2000年到2021年增加了近300%. 较小的孩子更容易受到这些可预防的药物错误的严重后果.
科学领域:
- 儿科毒理学 儿科毒理学
- 药物监督 药物监督 药物监督
- 公共卫生 公共卫生
背景情况:
- 注意缺陷/多动症 (ADHD) 药物被广泛用于年轻人.
- 药物管理中的治疗错误可能导致不良事件.
- 了解这些错误的趋势对于预防至关重要.
研究的目的:
- 分析20岁以下人群中与ADHD药物相关的非医院治疗错误的特征和趋势.
- 确定与这些错误相关的人口结构模式和常见情景.
- 评估结果的严重程度和影响结果的因素.
主要方法:
- 从2000年到2021年对国家毒物数据系统 (NPDS) 数据库的分析.
- 包括所有报告的非医院治疗的ADHD药物相关的治疗错误在20岁以下的个体.
- 使用美国人口普查数据计算基于人口的税率.
主要成果:
- 从2000年到2021年,每年报告给中毒中心的ADHD药物错误增加了近300%.
- 大多数错误涉及6-12岁儿童 (66.6%),男性 (76.4%) 和安非他命 (50.5%).
- 年龄较小的儿童 (<6岁) 面临更高的严重医疗结果 (OR=2.1) 和医疗机构入院 (OR=3.4) 的风险.
- 常见的错误包括双重剂量 (53.9%) 和意外摄入他人的药物 (13.4%).
结论:
- 严重上升的ADHD药物错误表明增加了处方,并突出了关键的公共卫生问题.
- 可预防的错误强调了需要加强患者和护理人员教育的必要性.
- 建议改进防儿童包装和药物跟踪系统,以减轻风险.
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