在接受子宫内授精的患者中,肥胖和生育能力之间的关联
LaTasha B Craig1, Christen L Jarshaw1, Karl R Hansen1
1Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
F&S reports
|September 18, 2023
概括
体重指数 (BMI) 在子宫内授精 (IUI) 周期中没有影响活产率. 然而,肥胖可能会降低患有排卵功能障碍的妇女接受IUI的临床怀孕率.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 不孕研究 不孕研究 不孕研究
- 肥胖问题研究研究
背景情况:
- 体重指数 (BMI) 是生殖健康的一个关键因素.
- 以前的研究表明,高BMI可能会对生育治疗产生负面影响.
- 体重指数对子宫内授精 (IUI) 结果的具体影响需要进一步调查.
研究的目的:
- 调查身体质量指数 (BMI) 和子宫内授精 (IUI) 后的生育结果之间的关联.
主要方法:
- 在一个以学术为基础的生育诊所进行了一项回顾性队列研究.
- 分析了2007年7月至2012年5月期间对661名女性进行的1959次IUI周期的数据.
- 活产率 (LBR),阳性怀孕测试和临床怀孕率 (CPRs) 被评估为主要和次要结局.
主要成果:
- 每个IUI周期的活产率 (LBR) 在所有BMI亚组中都相似,包括正常体重和肥胖类 (I,II,III).
- 与正常BMI女性相比,超重女性的怀孕率和心肺复苏率增加.
- 第三类肥胖妇女的怀孕率有所增加,但肥胖与排卵功能障碍妇女的CPR减少有关,而在没有排卵功能障碍的妇女中增加了CPR.
结论:
- 在IUI后的活产率似乎不受BMI的影响,与体外受精 (IVF) 研究的发现形成鲜明对比.
- 肥胖可能会对接受IUI的排卵功能障碍妇女的临床怀孕率产生负面影响.
- 由排卵功能对潜在效果的修改需要进一步调查,以了解观察到的差异.
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