阿波罗起:印度急性结膜炎疫情,2022年
N Venkatesh Prajna1, Lalitha Prajna1, Vishnu Teja1
1Aravind Eye Hospital, Madurai, India.
概括
泰米尔纳德邦的2022年结膜炎疫情是由共同流通的Coxsackievirus A24v和人类腺病毒D引起的.这项研究强调了元基因组测序在传染病爆发期间识别病原体的实用性.
科学领域:
- 眼科医生 眼科 眼科
- 病毒学 病毒学
- 传染性疾病 传染性疾病
背景情况:
- 结膜炎的爆发是一个重大的公共卫生挑战.
- 准确和快速的病原体鉴定对于有效的疫情控制至关重要.
研究的目的:
- 为了确定2022年印度泰米尔纳德邦膜炎疫情的致病原体.
- 为了研究不同病毒病原体的共同循环.
主要方法:
- 涉及急性传染性结膜炎患者的前性研究.
- 收集和处理前鼻和结膜样本.
- 甲基因组RNA深度测序 (RNA-seq) 用于病原体检测.
主要成果:
- 在97%的被测序患者 (28/29) 中发现了病原体.
- 考克萨基病毒A24v是主要的病原体 (23/29),其次是人类腺病毒D (5/29).
- 在感染两种病毒的患者中观察到出血结膜,尽管这不是主要症状.
结论:
- 考克萨基病毒A24v和人类腺病毒D在2022年爆发期间共同传播.
- 两种病毒感染的临床表现相似.
- 甲基因组测序为在疫情爆发时对病原体进行无偏的监测提供了一个有价值的工具.
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