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Updated: Jul 16, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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预测和克服癌症治疗中对CDK9抑制剂的耐药性

Chen Hu1,2, Lijuan Shen1,3, Fengming Zou1,2

  • 1Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.

Acta pharmaceutica Sinica. B
|September 18, 2023
PubMed
概括

在CDK9 (循环素依赖激酶9) 中发生的新突变导致对癌症药物的耐药性. 研究人员确定了这种突变,并开发了一种新化合物来克服这种抵抗力,为未来的癌症治疗提供了希望.

关键词:
获得的耐药性突变.BAY12511522 这是一个很好的例子.这是一种CDK9抑制剂.单个核酸的多态性.转录 转录 转录 转录

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