了解成人喘与冠状动脉疾病之间的联系:叙述性审查
Vasudha S Garg1, Mihir H Sojitra2, Tyagi J Ubhadiya1
1Department of Internal Medicine, Civil Hospital Ahmedabad, Ahmedabad, IND.
Cureus
|September 18, 2023
概括
喘和冠状动脉疾病 (CAD) 分享炎症途径. 失控的喘会增加心肌梗塞的风险,但药物对CAD的影响需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
背景情况:
- 喘涉及慢性呼吸道炎症,可能导致全身炎症和心血管疾病.
- 冠状动脉疾病 (CAD) 事件受到来自持续性肺炎的全身炎症的影响.
研究的目的:
- 审查喘患者的CAD风险因素.
- 阐明喘和CAD之间联系的机制.
- 检查喘特征和治疗对CAD发展的影响.
主要方法:
- 对喘,全身炎症和心血管结果研究的文献综述.
- 分析连接喘和动脉样硬化的内在 (炎症) 和外在 (缺氧,动脉节律失常) 途径.
- 检查有关喘控制,呼吸功能和心血管风险的证据.
主要成果:
- 成人发作的喘与增加的CAD和中风风险有关.
- 炎症,缺氧和动脉节律失常是连接喘和动脉样硬化的关键途径.
- 失控的喘与较高的心肌梗塞 (MI) 风险相关;呼吸功能受损是致命的MI和心血管死亡 (CVD) 的风险因素.
- β-2-激动剂和口服葡萄糖皮质类药物可能会增加CAD风险,尽管一些研究发现活跃喘患者没有与药物相关的MI风险.
结论:
- 喘和CAD通过共享的炎症和血管机制相互联系.
- 控制喘和呼吸功能是喘患者心血管风险的关键决定因素.
- 需要进一步的研究来澄清喘特征和抗喘药物在CAD发展中的作用.
相关概念视频
Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Asthma: Pathogenesis and Management
439
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
439
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Coronary Artery Disease I: Introduction
20
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
20


