结核病死亡人数:结核病相关和非结核病相关死亡人数之间的差异
Yun-Jeong Jeong1, Jae Seuk Park2, Hyung Woo Kim3
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
Frontiers in public health
|September 18, 2023
概括
鉴定结核病 (TB) 致死原因对于降低死亡率至关重要. 这项研究发现,与结核病相关的死亡与老年,低BMI和特定症状有关,而非结核病死亡则涉及并发症.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战,导致全球大量的发病率和死亡率.
- 降低结核病死亡率的有效策略需要清楚了解直接死亡原因和相关风险因素.
研究的目的:
- 确定结核病 (TB) 患者死亡的直接原因.
- 分析结核病患者与结核病相关和非结核病相关死亡率相关的风险因素.
主要方法:
- 韩国国家监控系统数据的回顾性分析 (2019年1月 - 2020年12月).
- 包括12340名被诊断患有结核病的患者.
- 与死亡率相关的临床特征,并发症,放射和微生物学发现的分析.
主要成果:
- 总体死亡率为10.6%;结核病相关死亡占结核病死亡总数的21.3%.
- 与结核病相关的死亡预测因素:年龄较大,体重指数较低,呼吸不良,发烧,虚弱,双边放射图案,AFB阳性涂抹.
- 非结核病相关死亡预测因素:年龄较大,男性性别,低BMI,并发病 (心脏,肝脏,脏,中枢神经系统),中枢神经系统结核病,呼吸障碍,虚弱,双边放射图案.
结论:
- 具体死因分析对于识别高风险结核病患者至关重要.
- 密集监测高疾病负担和并发症的结核病患者对于降低死亡率至关重要.
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