中部和四肢周长与所有原因死亡率和心血管死亡率的关联:一个队列研究
Jiajun Liu1,2, Xueshan Jin3, Ziyi Feng1,2
1Department of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Frontiers in cardiovascular medicine
|September 18, 2023
概括
中部肥胖,以腰围 (WC) 衡量,增加死亡风险. 用手臂周长 (AC),小腿周长 (CC) 和大腿周长 (TC) 测量的极端肥胖与较低的死亡率有关.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心血管健康 心血管健康
背景情况:
- 中心肥胖是糖尿病,心血管疾病 (CVD) 和癌症的已知危险因素.
- 极端肥胖和死亡率之间的关联仍未得到充分研究.
- 这项研究调查了中部和四肢肥胖对死亡率的影响.
研究的目的:
- 量化腰围 (WC),手臂周长 (AC),小腿周长 (CC) 和大腿周长 (TC) 对所有原因和心血管疾病死亡率的影响.
- 评估极端肥胖度作为潜在的预后工具.
- 分析与肥胖相关的性别特异性死亡风险.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) (1999-2006) 的数据,其中有19,735名参与者.
- 采用COX比例危险回归模型来评估死亡风险.
- 根据性别进行了分层分析,并根据人口统计学因素进行了调整.
主要成果:
- 较高的WC显着与增加全因死亡风险有关.
- 较高的AC,CC和TC显著与所有原因死亡风险的降低有关.
- 在调整混因素后,这些关联仍然存在.
结论:
- 中央肥胖指标 (WC) 与全因和心血管疾病死亡率有积极关联.
- 极端肥胖度 (AC,CC,TC) 与所有原因和心血管疾病死亡率有负面关联.
- 在一般人群中,AC,CC和TC显示出作为预后指标的潜力.
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