益生菌摄入对儿童便秘的影响:一个总体综述
Mingyang Dong1, Yuting Wu1, Mengzhen Zhang2
1Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, China.
Frontiers in nutrition
|September 18, 2023
概括
功能性便秘 (FC) 的儿童摄入益生菌显著改善了治疗成功率和肠道排便频率. 这些益生菌是安全的,不会增加不良事件,为管理儿童便秘提供了有希望的方法.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 微生物组研究 微生物组研究
背景情况:
- 功能性便秘 (FC) 是一个常见的儿科胃肠道疾病.
- 目前针对FC的治疗方法的疗效和潜在副作用各不相同.
- 益生菌在治疗儿科便秘中的作用需要全面评估.
研究的目的:
- 对现有证据进行全面的审查,以了解儿童对便秘的益生菌摄入量.
- 评估检查益生菌治疗儿科便秘的研究的质量,有效性和潜在偏差.
- 综合治疗成功,症状频率和不良事件的研究结果.
主要方法:
- 九个现有的系统性审查和元分析的系统性审查和元分析.
- 包括来自628篇文章的数据.
- 分析了七个有效性指标和儿科FC的不良反应发生率.
主要成果:
- 益生菌摄入显著改善了患有FC的儿童的治疗成功率和排便频率.
- 使用益生菌观察到便秘的复发率下降.
- 没有发现益生菌摄入与腹部疼痛,便一致性,排便疼痛或便失禁有重大关联.
- 益生菌显示出良好的安全性,没有增加不良反应的发生率.
结论:
- 益生菌有效改善功能性便秘的儿童的关键结果,包括治疗成功和排便频率.
- 益生菌补充剂是安全的,并且在患有便秘的儿科患者中耐受良好.
- 进一步的研究可能会探索特定的益生菌菌株及其针对性对便秘相关症状的影响.
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