长期运动训练和健康受试者的炎症生物标志物:随机对照试验的元分析
Ya-Hai Wang1, Jingwang Tan2, Huan-Huan Zhou3
1College of Arts and Physical Education, Nanchang Normal College of Applied Technology, Nanchang, China.
在健康的成年人中,长期的运动训练显著降低了IL-6,CRP和TNF-alpha等炎症生物标志物. 适度强度和持续时间超过12周可以增强这些抗炎作用.
科学领域:
- 运动生理学 运动生理学
- 免疫学 免疫学 免疫学
- 生物标志物研究的研究.
背景情况:
- 慢性炎症与各种疾病有关.
- 运动训练是一种潜在的非药物干预来调节炎症.
- 了解不同运动方式对炎症标志物的影响,对公共卫生至关重要.
研究的目的:
- 对长期运动训练 (ET) 对健康个体炎症生物标志物的影响进行元分析.
- 评估有氧,抵抗和多元组件ET的影响.
- 确定影响ET抗炎作用的因素.
主要方法:
- 在七个数据库中系统搜索随机对照试验 (RCT) 到2023年5月.
- 进行了随机效应元分析,子组分析和元回归.
- 包括38个RCT与2,557名健康受试者.
主要成果:
- 长期的ET显著降低了互白素-6 (IL-6),C反应蛋白 (CRP) 和瘤死因子α (TNFα) 的水平.
- 亚组分析表明,对于超过12周的ET和中等强度的ET,抗炎作用更大.
- 超回归显示,增加运动强度会减轻CRP的减少.
结论:
- 长期的运动训练在健康人群中显示出显著的抗炎作用.
- 适度强度和持续时间超过12周与增强的抗炎功效有关.
- 运动强度在调节CRP对训练的反应方面发挥着作用.
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