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Updated: Jun 14, 2026

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选择具有HMGA干扰活性和癌细胞细胞毒性的天然化合物

Mattia Mori1, Francesca Ghirga2, Beatrice Amato3

  • 1Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena 53100, Italy.

ACS omega
|September 18, 2023
PubMed
概括

研究人员确定了与富含AT的DNA序列结合的天然化合物,可能阻断高流动性A组 (HMGA) 蛋白质. 索罗素C显示出有前途的HMGA/DNA取代活性和对癌细胞的细胞毒性.

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Inhibition of Cdk Activity02:34

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