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相关概念视频

Biological Effects of Radiation02:59

Biological Effects of Radiation

15.5K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.5K
Radiation: Applications01:17

Radiation: Applications

1.2K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
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Absorption of Radiation01:05

Absorption of Radiation

761
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
761
Radiation Pressure: Problem Solving01:09

Radiation Pressure: Problem Solving

394
The radiation pressure applied by an electromagnetic wave on a perfectly absorbing surface equals the energy density of the wave. The wave's momentum also gets transferred to the surface when an electromagnetic wave is entirely absorbed by it. The rate at which momentum is transmitted to an absorbing surface perpendicular to the propagation direction equals the force on the surface.
The average value of the rate of momentum transfer divided by the absorbing area represents the average force...
394
Mutations01:35

Mutations

38.2K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
38.2K

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相关实验视频

Updated: Jul 16, 2025

An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
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An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes

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在安全的,基于云的在线环境中确定辐射暴露.

Ben C Shirley1, Eliseos J Mucaki2, Joan H M Knoll1,3

  • 1CytoGnomix Inc., 60 N. Centre Rd., London Ontario N5X 3X5, Canada.

Radiation protection dosimetry
|September 18, 2023
PubMed
概括

基于网络的ADCI在线系统使用双中心染色体 (DC) 试验快速估计辐射暴露. 这加快了对辐射事件的分析,改善了分拣和患者护理.

科学领域:

  • 辐射生物学 辐射生物学
  • 医学物理 医学物理
  • 计算毒理学计算毒理学

背景情况:

  • 对辐射暴露的快速评估对于放射性事件后的有效分拣至关重要.
  • 二心染色体 (DC) 试验是生物剂量计的黄金标准,但可能耗时.
  • 现有的自动化系统需要专门的硬件,限制了可访问性.

研究的目的:

  • 通过使用自动双中心染色体识别和剂量估计系统 (ADCI) 提高辐射剂量估计的可访问性和速度.
  • 开发一个安全的,网络流媒体平台 (ADCI在线) 为全球访问辐射暴露评估.
  • 在基于云的环境中确保数据和软件的完整性.

主要方法:

  • 开发ADCI在线,一个安全的网络流媒体平台,利用基于云的系统.
  • 分离基于云的数据和软件,直到用于剂量估计的链接.
  • 与专用硬件ADCI系统对剂量估计的验证.
  • 通过图像处理,校准曲线生成和测试样品剂量估计来评估性能.

主要成果:

  • ADCI在线提供与专用ADCI系统相同的剂量估计.
  • 该系统在不到2天内完成了9个样本的图像处理,校准和剂量估计.

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An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
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Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
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Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

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  • 云环境中的多个克隆软件实例将剂量估计加速到临床相关的时间框架.
  • 结论:

    • ADCI在线显著扩大了可访问性,并加速了辐射剂量估计.
    • 该平台可以缓解中等到大规模辐射事件期间的分析瓶.
    • 该系统为应急准备中的生物剂量测量提供了可扩展和高效的解决方案.