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创伤性脑损伤后的管理模式和结果与相关的脑血管损伤

Matthew C Findlay¹, Gabriela Sarriera-Valentin², Emma R Earl¹

¹School of Medicine, University of Utah, Salt Lake City , Utah , USA.

|September 18, 2023

概括

在患有创伤性脑损伤 (TBI) 的患者中,脑血管损伤 (BCVI) 增加了严重程度的中风风险. 阿司匹林使用与降低死亡率有关,但高度的BCVI相关中风往往发生急性.

科学领域:

神经学神经学
创伤外科手术创伤外科
血管外科血管外科

背景情况:

脑血管损伤 (BCVI) 在创伤性脑损伤 (TBI) 中很常见.
预防神经系统并发症的BCVI的最佳管理仍然不确定.
这项研究调查了TBI患者BCVI的治疗结果和治疗策略.

研究的目的:

在TBI患者中描述BCVI护理模式.
根据BCVI等级评估不良结果 (中风,缺陷,死亡).
评估BCVI和TBI的治疗方法.

主要方法:

对323名患有BCVI的TBI患者 (2016-2020) 的回顾性分析.
收集关于特征,治疗和结果的数据.
进行单变量和多变量分析以评估风险因素和治疗疗效.

主要成果:

较高的BCVI等级与中风风险增加相关 (例如,IV级或19.6级与I级).
大多数中风发生在急性中 (<24小时),特别是在高度伤害中.
阿司匹林使用 (低剂量或高剂量) 与死亡率降低有关 (OR 0.1).

结论:

在TBI患者中,BCVI严重程度直接增加了中风和发病风险.
对于高度的BCVI相关中风,急性管理至关重要.
目前的策略似乎能减轻风险,以较少的晚期中风为证.

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Traumatic Brain Injury l: Introduction

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DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...